KEGG   REACTION: R03088
Entry
R03088                      Reaction                               
Definition
Estradiol-17beta + H+ + Oxygen + NADH <=> 2-Hydroxyestradiol + NAD+ + H2O
Equation
Reaction class
RC00001  C00003_C00004
RC00046  C00951_C05301
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R03088  Estradiol-17beta + H+ + Oxygen + NADH <=> 2-Hydroxyestradiol + NAD+ + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.1
   R04122  Alkane <=> ROH
    R03088  Estradiol-17beta <=> 2-Hydroxyestradiol
Orthology
K07410  cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]

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